"Gene expression profiles of human proximal tubular epithelial cells in proteinuric nephropathies.”


Table 1.

Of the 230 genes found to be differentially regulated between patients and controls, 168 were assignable to gene-ontology terms.

Table 2.

Clinical and histological characteristics of patients and controls.

Table 3.

Information on primary antibodies for immunohistochemistry.

Webtable 1.

62 genes of the 230 separating patients from controls are not assigned to GO terms. They are mostly ORFs, hypothetical proteins and ESTs.

Webtable 2.

Enriched PANTHER ontology categories, which are significantly upregulated in proteinuric patients.

Webtable 3.

Enriched PANTHER ontology categories, which are significantly downregulated in proteinuric patients.

Webtable 4.

Length of amplified RNA as analysed on Agilent BioanalyzerTM.

Figure 1.

Taqman real-time PCR analysis of five selected genes from table 1.

Figure 2a.

Immunohistochemistry: TSP-3 in controls.

Figure 2b.

Immunohistochemistry: TSP-3 in patients.

Figure 3a.

Immunohistochemistry: BMP-7 in controls.

Figure 3b.

Immunohistochemistry: BMP-7 in patients.

Figure 4.

Alkaline phosphatase staining of proximal tubular cells using NBT/BCIP.

Webfigure 1.

Unsupervised hierarchical cluster analysis of 19 patient and 5 control samples.
Dr. Michael Rudnicki
Medical University Innsbruck
Department of Internal Medicine IV, Nephrology und Hypertension
Anichstrasse 35, A-6020 Innsbruck
Tel: +43 512 504 81337, Fax: +43 512 504 25857